Faculty of Health Sciences
https://hdl.handle.net/10155/388
Faculty of Health Sciences (FHSCI)2024-03-28T15:04:27ZIntroduction to target trial emulation in rehabilitation: a systematic approach to emulate a randomized controlled trial using observational data
https://hdl.handle.net/10155/1762
Introduction to target trial emulation in rehabilitation: a systematic approach to emulate a randomized controlled trial using observational data
Côté, Pierre
ehabilitation providers and policymakers need valid evidence to make informed decisions about the healthcare needs of the population. Whenever possible, these decisions should be informed by randomized controlled trials (RCTs). However, there are circumstances when evidence needs to be generated rapidly, or when RCTs are not ethical or feasible. These situations apply to studying the effects of complex interventions, including rehabilitation as defined by Cochrane Rehabilitation. Therefore, we explore using the target trial emulation framework by Hernán and colleagues to obtain valid estimates of the causal effects of rehabilitation when RCTs cannot be conducted. Target trial emulation is a framework guiding the design and analysis of non-randomized comparative effectiveness studies using observational data, by emulating a hypothetical RCT. In the context of rehabilitation, we outline steps for applying the target trial emulation framework using real world data, highlighting methodological considerations, limitations, potential mitigating strategies, and causal inference and counterfactual theory as foundational principles to estimating causal effects. Overall, we aim to strengthen methodological approaches used to estimate causal effects of rehabilitation when RCTs cannot be conducted.
2024-02-01T00:00:00ZSynthesizing existing evidence and leveraging expert opinions to develop a university, for-profit, and not-for-profit organization partnership model to address health professions education gaps through simulation-based education
https://hdl.handle.net/10155/1751
Synthesizing existing evidence and leveraging expert opinions to develop a university, for-profit, and not-for-profit organization partnership model to address health professions education gaps through simulation-based education
Siraj, Samyah
Healthcare providers in rural and remote (R&R) areas of Canada do not have the same access to skills development and maintenance opportunities as those in urban areas. Simulation-based education (SBE) is an optimal technique to allow healthcare providers to develop and maintain skills. However, SBE is mainly limited to universities or hospital-based research laboratories in urban areas. The purpose of this thesis was to develop a partnership model between university research laboratories, for-profit organizations, and not-for-profit organizations to diffuse SBE into R&R communities. Phase A aimed to identify the problem and present a solution through an editorial paper. Phase B consisted of a scoping review to understand the current landscape of literature. Phase C was a qualitative descriptive study interviewing stakeholders to understand their perspective experiencing the partnership process. All three phases were consolidated to create a partnership model to deliver simulation solutions to R&R healthcare settings.
2023-12-01T00:00:00ZPrevalence of Unmet Rehabilitation Needs Among Canadians Living With Long-term Conditions or Disabilities During the First Wave of the COVID-19 Pandemic
https://hdl.handle.net/10155/1744
Prevalence of Unmet Rehabilitation Needs Among Canadians Living With Long-term Conditions or Disabilities During the First Wave of the COVID-19 Pandemic
De Souza, Astrid; Wang, Dan; Wong, Jessica J.; Furlan, Andrea D.; Hogg-Johnson, Sheilah; Macedo, Luciana; Mior, Silvano; Côté, Pierre
Describe the prevalence of unmet rehabilitation needs among a sample of Canadians living with long-term conditions or disabilities during the first wave of the COVID-19 pandemic
2023-01-01T00:00:00ZEffect of neck muscle vibration on upper limb sensorimotor integration and motor performance
https://hdl.handle.net/10155/1743
Effect of neck muscle vibration on upper limb sensorimotor integration and motor performance
Tabbert, Hailey
Upper limb control depends on accurate internal models of the position of the limbs relative to the head and neck. The cerebellum is heavily involved in SMI of neck sensory inputs and motor learning; therefore, it is likely that altered neck sensory input will impact cerebellar processing. However, it is unclear whether acute models of altered afferent input from vibration impacts SMI, somatosensory processing, and proprioception.
Study one used SEPs to investigate the effects of neck muscle vibration on SMI and motor learning while study two used an elbow repositioning task to investigate its effects on upper limb proprioception. Vibration led to differential changes in SEP peaks associated with cerebellar processing and motor skill acquisition, and changes in upper limb accuracy.
This thesis suggests that neck muscle vibration impacts cerebellar processing and motor control, likely due to vibration-induced alterations in body schema leading to neuroplastic adaptations and reduced accuracy.
2022-07-01T00:00:00Z