Now showing items 1-6 of 6
Isolation and partial characterization of three members of the GGR-1 family in the parasitic nematode Haemonchus contortus
Haemonchus contortus is a blood sucking parasitic nematode that infects ruminant animals. These parasites are of significant economic importance as they are estimated to cost the agricultural industry billions of dollars ...
A molecular characterization of agonists that bind to Hco-UNC-49, a GABA-gated chloride channel from Haemonchus contortus
Haemonchus contortus is a blood feeding parasitic nematode infecting ruminants causing anemia and poor health at great economic cost. The ability to pharmaceutically control infection has been challenged by the rapid ...
Molecular characterization of the binding site of nematode GABA-A receptors
Haemonchus contortus is a parasitic nematode that is controlled in large part by nematocidal drugs that target receptors of the parasitic nervous system. Hco-UNC-49 is a nematode GABA receptor that has a relatively low ...
Molecular characterization of GABA receptor subunits from the parasitic nematode Haemonchus contortus
Haemonchus contortus is a parasitic nematode that is controlled by several nematocides which target ion channels. We have identified two H. contortus ion channel genes, Hcounc- 49B and C that encode two GABA-gated chloride ...
An examination of interacting residues in the GABA-gated ion channel UNC-49 within the parasitic nematode Haemonchus contortus
Haemonchus contortus is a blood-feeding parasitic nematode that infects ruminant animals around the world, including those with significant economic importance such as cattle, sheep, and goats. UNC-49 is a GABA-gated ...
Investigation into the role of binding loop E on the function of the nematode cys-loop GABA receptor.
Haemonchus contortus is a parasitic nematode that infects the abomasum of ruminants. While several classes of anthelmintic drugs exist to control nematode infections, H. contortus is resistant to all of them. Therefore, ...