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Molecular characterization of GABA receptor subunits from the parasitic nematode Haemonchus contortus
(2009-08-01)
Haemonchus contortus is a parasitic nematode that is controlled by several nematocides
which target ion channels. We have identified two H. contortus ion channel genes, Hcounc-
49B and C that encode two GABA-gated chloride ...
Examination of intramolecular interactions between residues of the cys-loop GABA receptor Hco-UNC-49 from Haemonchus contortus
(2016-01-01)
Haemonchus contortus is a parasitic nematode known to infect ruminant animals such as sheep, goats and cattle. Despite several different anthelmintic drugs available to control the spread of this infection, H. contortus ...
Investigation into the role of binding loop E on the function of the nematode cys-loop GABA receptor.
(2014-12-01)
Haemonchus contortus is a parasitic nematode that infects the abomasum of
ruminants. While several classes of anthelmintic drugs exist to control nematode infections,
H. contortus is resistant to all of them. Therefore, ...