Browsing Doctoral Dissertations by Title
Now showing items 25-44 of 71
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The ecotoxicological effects of metformin and its metabolite, guanylurea, on Japanese medaka (Oryzias latipes)
(2018-08-01)Human pharmaceutical waste threatens many natural processes of non-target aquatic organisms, through the introduction of such contaminants into the environment. Pharmaceuticals are a large and diverse groups of medicinal ... -
The effect of experimental pain on neural function and motor learning
(2017-04-01)This thesis investigated whether acute experimental pain interacts with motor learning acquisition to create adaptive and maladaptive changes in neural function. The first study consisted of two experiments where we ... -
The Effects of 17α-Ethinylestradiol (EE2) and Hydroxypropyl-β-Cyclodextrin (HPβCD) on the heart rate and metabolism of Embryonic Japanese Medaka (Oryzias latipes)
(2019-04-01)Estrogen toxicity has been an area of priority in aquatic toxicology over the last 20 years. The toxicity of a known estrogen mimic, 17α-ethinylestradiol (EE2), has been attributed to classical estrogen signaling within ... -
Effects of dietary fermentable material on innate and adaptive immune measures in male and female rats under resting and immunized conditions
(2015-02-01)Sex-based differences in immune parameters are well recognized, and recent evidence suggests differences in microbiota composition between sexes, necessitating assessment of effects of dietary fermentable material (DFM) ... -
Elucidation of the lipid degradation process in soft tissue and fluid during decomposition, in the presence and absence of insects.
(2014-08-01)Decomposition has been extensively studied in the presence of insects, however the process in the absence of insects has been considerably less documented. In this study, the decomposition process was compared between ... -
Examining swim bladder inflation failure as a toxicological endpoint in Japanese medaka (Oryzias latipes)
(2017-11-01)Inadequate swim bladder inflation, while not being lethal itself, can have serious long-term effects on fish populations. Many environmental contaminants can inhibit swim bladder inflation of larval fish. Understanding how ... -
Forward and reverse genetic approaches to investigate cellulose biosynthesis in Physcomitrium patens
(2021-04-01)Cellulose biosynthesis is a common feature of land plants and involves multimeric complexes composed of cellulose synthase A (CESA) proteins and other structural proteins. The exact stoichiometry of CESA proteins and ... -
Forward genetic analysis of cellulose biosynthesis inhibitor resistance and wall hydrolysis sensitivity.
(2014-09-01)The functional analysis of components involved in cellulose biosynthesis is central in understanding cell wall assembly and structure in plants. We conducted screens using the herbicides, isoxaben and flupoxam which inhibit ... -
Forward screening for herbicide resistance in Arabidopsis thaliana and the monocot species Triticum aestivum
(2019-06-01)Cellulose is the primary structural component of plant cell walls and is composed of β-1,4-glucan chains. The cellulose synthesis complex is composed of multiple cellulose synthases (CESAs), which work together to extend ... -
A framework for privacy-preserving data sharing in smart grid
(2016-01-01)While smart grid introduces a lot of enhancements to the traditional power grid and improves managing and controlling consumers demands, it also introduces security and privacy issues. Therefore, failure to address them ... -
Functionalized carbon surfaces for clean electrochemical energy systems
(2022-03-01)The development and implementation of clean energy technologies is the way to overcome the global energy crisis and reduce pollution. Therefore, new energy solutions are rapidly needed. Fuel cells (FCs) may become one such ... -
A graph-based real-time spatial sound framework
(2020-01-01)Given the importance of sound, and our ability to localize sound sources in three-dimensions in the real world, incorporating spatial sound in virtual environments can help increase realism, improve the sense of “presence”, ... -
Identification and characterization novel of cystine-loop ligand- gated chloride channels from Dirofilaria immitis: pharmacological analysis and novel compound screening
(2023-12-01)Dirofilaria immitis, otherwise known as heartworm, is a parasite that infects the hearts of dogs and causes serious health consequences. While preventative treatments are available drug resistance is developing at an ... -
Immunomodulatory activity of Lacticaseibacillus rhamnosus R0011: analysis of secretome-mediated impacts on innate immune outcomes in intestinal epithelial cells and antigen presenting cells
(2021-12-01)Certain lactic acid bacteria (LAB), such as Lacticaseibacillus rhamnosus R0011, are associated with immune modulatory activities including down-regulation of pro-inflammatory gene transcription and expression. While host ... -
Impact of neck muscle fatigue on upper limb sensorimotor integration
(2019-08-01)Neck muscles have a high density of sensory receptors which project to the central nervous system, and have important role in sensory motor integration (SMI). The cerebellum is important for SMI and it is known to undergo ... -
The impact of restricted ration and chemical stressors on Rainbow trout (Oncorhynchus mykiss) and American flagfish (Jordanella floridae)
(2017-12-01)This research aimed to increase the understanding of the impact of multiple factors including both environmental and chemical stressors and their effects on fish survival, growth, and reproduction. Rainbow trout (Oncorhynchus ... -
Influence of dietary interventions on the immune system: an investigation of the impact of omega-3 fatty acids, dietary fermentable materials and high energy diets
(2016-12-01)Dietary interventions vary in ability to influence immune activity. Separate investigations were conducted to determine the immune impact of omega-3 fatty acids, dietary fermentable materials (DFM) and high energy (HE) ... -
Integrated traffic analysis and visualization for future road events
(2023-04-01)The existing traffic simulation methods are limited to specific synthetic scenarios. In addition, the natural structure of traffic and accident data requires modeling the dependent observations on multiple levels. Therefore, ... -
Investigating the distribution of Nitellopsis obtusa in Ontario Lakes and its role as an ecosystem engineer
(2021-08-01)Nitellopsis obtusa is a non-native macrophyte introduced into the Laurentian Great Lakes in 1974. Over the last decade, increasing reports emerged for N. obtusa within lakes in the Great Lakes Basin. Despite N. obtusa being ... -
Leveraging vehicular cloud computing through location and request prediction
(2023-04-01)In recent years, the implementation of Vehicular Ad-hoc networks (VANET) has been acknowledged as a promising solution for monitoring road conditions. Despite the many benefits they can bring to society, the growing demand ...