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The synthesis and in vitro evaluation of siRNAs modified at the backbone with a novel triazole-based internucleotide linkage and abasic alkyl-chain linkages of varying length
(2013-04-01)
For over a decade, the use of double-stranded short interfering RNAs (siRNAs) to silence the expression of genes associated with disease at the translational level has gained much attention. Using a highly conserved ...
Determining the impact of carrion decomposition on soil microbial activity levels and community composition.
(2013-12-01)
The ubiquitous nature of microorganisms and their specificity to certain locations make them potentially useful for forensic investigators. Advances in microbial profiling techniques have made it possible to compare microbial ...
Analysis of the volatile organic compounds produced by the decomposition of pig carcasses and human remains
(2013-03-01)
Complex processes of decomposition produce a variety of chemicals as soft tissues and their component parts are degraded. Among others, these decomposition by-products include volatile organic compounds (VOCs) responsible ...