Search
Now showing items 21-30 of 69
The synthesis and in vitro evaluation of siRNAs modified at the backbone with a novel triazole-based internucleotide linkage and abasic alkyl-chain linkages of varying length
(2013-04-01)
For over a decade, the use of double-stranded short interfering RNAs (siRNAs) to silence the expression of genes associated with disease at the translational level has gained much attention. Using a highly conserved ...
Examining swim bladder inflation failure as a toxicological endpoint in Japanese medaka (Oryzias latipes)
(2017-11-01)
Inadequate swim bladder inflation, while not being lethal itself, can have serious long-term effects on fish populations. Many environmental contaminants can inhibit swim bladder inflation of larval fish. Understanding how ...
The modification of fuel cell-based breath alcohol sensor materials to improve water retention of sensing performance
(2016-03-01)
Fuel cell based breath alcohol sensors (BrASs) are one of the most important tools used by law enforcement today. While these devices are used globally, they all suffer from a common deficiency: reliance on water. The ...
A deep learning approach to focal cortical dysplasia segmentation in children with medically intractable epilepsy
(2021-08-01)
Paediatric epilepsy is one of the most common neurological disorders and has major impact on the cognition and quality of life of children. Focal Cortical Dysplasia (FCD) is one of the most common causes of medically ...
Community-oriented architecture for smart cities
(2017-12-01)
With the widespread use of smartphone devices, a surge in mobile sensing, progress in wireless communication and networking techniques, as well as the development of the Internet of Things (IoT) and cloud computing, ...
Nanostructured materials for photovoltaics and microwave electronics: methods and applications
(2017-04-01)
Nanoscale particles and thin layers are today used for a variety of applications to make industrial products lighter, stronger or more conductive. This study investigates synthesis, characterization and application of ...
Towards efficient and scalable computer vision systems
(2018-01-01)
There is a large growth in hardware and software systems capable of producing vast amounts of image and video data. These systems are rich sources of continuous and possibly infinite image and video streams. This motivates ...
A graph-based real-time spatial sound framework
(2020-01-01)
Given the importance of sound, and our ability to localize sound sources in three-dimensions in the real world, incorporating spatial sound in virtual environments can help increase realism, improve the sense of “presence”, ...
Towards implicit learning of system-assigned authentication tokens
(2018-02-01)
People tend to choose predictable passwords which are vulnerable to guessing attacks. To combat the security issue, system-assigned authentication keys were proposed, but coming at a cost to memorability. In this thesis, ...
Comparing exercise responses to high intensity interval training between adults with and without asthma
(2020-06-01)
Exercise induced bronchoconstriction (EIBC) occurs in response to high ventilations during exercise, which cools and dries the airways, triggering an inflammatory cascade. High intensity interval training (HIIT) is associated ...