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Development of Non-covalent Chemical Probes for μ, δ and κ Opioid Receptors
(2020-12-01)
Opioids are well-known pain relievers and one of several therapeutic options for pain management. Although opioids are very effective analgesics, continued use and abuse can lead to physical dependence and withdrawal ...
Adaptive engagement of older adults’ fitness through gamification
(2017-07-01)
Older adults are often not physically active because they lack motivation, time, and/or physical ability. Not only does this impact the life of older adults, but it also affects society as a whole, because the cost of ...
Monolayer terpyridyl metal complexes for high-efficiency electrochromic materials
(2021-08-01)
Electrochromic materials (ECMs) can change their color with changes of applied electrochemical potential. Currently, the use of ECMs in the industry is limited to mainly inorganic metal oxides, conjugated conducting polymers, ...
The effect of experimental pain on neural function and motor learning
(2017-04-01)
This thesis investigated whether acute experimental pain interacts with motor learning acquisition to create adaptive and maladaptive changes in neural function. The first study consisted of two experiments where we ...
Analysis of resistance nodulation division efflux pumps in Acinetobacter baumannii
(2015-01-01)
Strains from Canadian hospitals were classified as A. baumannii, A. pitti, or A. osocomialis and the most commonly expressed resistance nodulation division (RND) efflux pump was adeFGH. A collection of A. baumannii isolates ...
Mechanisms by which exercise promotes cognitive function in both depressed and non-depressed individuals
(2017-12-01)
Major depressive disorder (MDD) is a debilitating disease characterized by low mood, memory deficits, poor sleep quality and alterations in biochemical markers associated with neuroplasticity. Less than half of MDD patients ...
Cognitive function during exertional heat stress assessed using traditional and serious game technology
(2016-06-01)
Firefighting is a physically demanding occupation requiring intermittent bouts of work resulting in increased levels of cardiovascular and thermal strain, while making decisions requiring higher order cognitive abilities ...
Determining the impact of carrion decomposition on soil microbial activity levels and community composition.
(2013-12-01)
The ubiquitous nature of microorganisms and their specificity to certain locations make them potentially useful for forensic investigators. Advances in microbial profiling techniques have made it possible to compare microbial ...
A secure and privacy-preserving incentive framework for vehicular cloud
(2018-04-01)
Vehicular Cloud Computing (VCC) plays a critical role in data generation where a large number of vehicles collect various kinds of sensing resources with large-volume features. While the information that should be collected ...
Towards molecular reconstruction in Coulomb explosion imaging
(2021-02-01)
The interaction of a fast laser with molecules at the femtosecond time scale, leads to the latter losing most of its valence electrons and become positively charged. The molecule which was initially in an equilibrium state, ...