Browsing Faculty of Science by Subject "Ligand-gated chloride channel"
Now showing items 1-3 of 3
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Examination of intramolecular interactions between residues of the cys-loop GABA receptor Hco-UNC-49 from Haemonchus contortus
(2016-01-01)Haemonchus contortus is a parasitic nematode known to infect ruminant animals such as sheep, goats and cattle. Despite several different anthelmintic drugs available to control the spread of this infection, H. contortus ... -
Investigation into the role of binding loop E on the function of the nematode cys-loop GABA receptor.
(2014-12-01)Haemonchus contortus is a parasitic nematode that infects the abomasum of ruminants. While several classes of anthelmintic drugs exist to control nematode infections, H. contortus is resistant to all of them. Therefore, ... -
Molecular characterization of GABA receptor subunits from the parasitic nematode Haemonchus contortus
(2009-08-01)Haemonchus contortus is a parasitic nematode that is controlled by several nematocides which target ion channels. We have identified two H. contortus ion channel genes, Hcounc- 49B and C that encode two GABA-gated chloride ...