Browsing Master Theses & Projects by Subject "Haemonchus contortus"
Now showing items 1-6 of 6
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An examination of interacting residues in the GABA-gated ion channel UNC-49 within the parasitic nematode Haemonchus contortus
(2017-10-01)Haemonchus contortus is a blood-feeding parasitic nematode that infects ruminant animals around the world, including those with significant economic importance such as cattle, sheep, and goats. UNC-49 is a GABA-gated ... -
Investigation into the role of binding loop E on the function of the nematode cys-loop GABA receptor.
(2014-12-01)Haemonchus contortus is a parasitic nematode that infects the abomasum of ruminants. While several classes of anthelmintic drugs exist to control nematode infections, H. contortus is resistant to all of them. Therefore, ... -
Isolation and partial characterization of three members of the GGR-1 family in the parasitic nematode Haemonchus contortus
(2019-08-01)Haemonchus contortus is a blood sucking parasitic nematode that infects ruminant animals. These parasites are of significant economic importance as they are estimated to cost the agricultural industry billions of dollars ... -
A molecular characterization of agonists that bind to Hco-UNC-49, a GABA-gated chloride channel from Haemonchus contortus
(2012-11-01)Haemonchus contortus is a blood feeding parasitic nematode infecting ruminants causing anemia and poor health at great economic cost. The ability to pharmaceutically control infection has been challenged by the rapid ... -
Molecular characterization of GABA receptor subunits from the parasitic nematode Haemonchus contortus
(2009-08-01)Haemonchus contortus is a parasitic nematode that is controlled by several nematocides which target ion channels. We have identified two H. contortus ion channel genes, Hcounc- 49B and C that encode two GABA-gated chloride ... -
Molecular characterization of the binding site of nematode GABA-A receptors
(2010-08-01)Haemonchus contortus is a parasitic nematode that is controlled in large part by nematocidal drugs that target receptors of the parasitic nervous system. Hco-UNC-49 is a nematode GABA receptor that has a relatively low ...