Browsing Electronic Theses and Dissertations by Title
Now showing items 1332-1351 of 1478
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Supporting student success with machine learning and visual analytics
(2019-08-01)Post secondary institutions have a wealth of student data at their disposal. This data has recently been used to explore a problem that has been prevalent in the education domain for decades. Student retention is a complex ... -
A survey of algebraic algorithms in computerized tomography
(2010-08-01)X-ray computed tomography (CT) is a medical imaging framework. It takes measured projections of X-rays through two-dimensional cross-sections of an object from multiple angles and incorporates algorithms in building a ... -
Synthesis and characterization of nanostructured catalysts for photovoltaic applications
(2013-07-01)The objective of this project was to investigate the effect of the morphology of titanium dioxide (TiO2) nanoparticles on the electron transport properties and light harvesting potential in a dye sensitized solar cell ... -
Synthesis and characterization of Pt/TiO2/C composite catalysts for fuel cells prepared using a glucose modifier
(2017-03-01)Catalysts in the electrodes of polymer exchange membrane fuel cells (PEMFCs) serve a critical function in reactions which can be used to generate electrical energy from chemical fuels. Pt nanoparticles are commonly dispersed ... -
Synthesis and characterization of purely sulphonated and composite membranes for high temperature fuel cells
(2010-04-01)Fuel cell technologies have developed high interest due to their ability to provide energy in an environmentally friendly method. Proton exchange membrane fuel cells (PEM-FCs) require a PEM for use, where the most accepted ... -
Synthesis and in vitro assessment of chemically modified siRNAs targeting BCL2 that contain 2'-ribose and triazole-linked backbone modifications
(2015-08-01)Short interfering RNAs (siRNAs) are biomolecules used for post-transcriptional gene regulation, and therefore hold promise as a future therapeutic by silencing gene expression of overexpressed deleterious genes. Chemically ... -
The synthesis and in vitro evaluation of chemically modified siRNAs that contain internal azobenzene derivative spacers for selective and tunable photocontrol of activity
(2017-08-01)Short interfering RNAs (siRNAs) are biopolymers that are used as post-transcriptional gene regulators and as a natural endogenous defense against attack from viruses. These molecules hold a great deal of interest as ... -
The synthesis and in vitro evaluation of short interfering RNA containing triazole functionalized sphingolipid-based derivatives
(2021-12-01)RNA Interference (RNAi) is a natural cellular process that silences the expression of a target gene in a sequence-specific manner by mediating targeted mRNA degradation. One of the main challenges in RNAi research is ... -
The synthesis and in vitro evaluation of short interfering RNAs that contain internal modified alkyl spacers
(2014-08-01)The ability to silence genes effectively at the pre-translational level through the use of short interfering ribonucleic acid (siRNA) has become a widely studied area since the discovery of the RNA interference pathway in ... -
The synthesis and in vitro evaluation of siRNAs modified at the backbone with a novel triazole-based internucleotide linkage and abasic alkyl-chain linkages of varying length
(2013-04-01)For over a decade, the use of double-stranded short interfering RNAs (siRNAs) to silence the expression of genes associated with disease at the translational level has gained much attention. Using a highly conserved ... -
The synthesis and in vivo evaluation of chemically modified siRNAs that contain red-shifted internal azobenzene derivative spacers for selective and tunable photocontrol of activity without UV light
(2021-08-01)Short interfering RNAs (siRNAs) are biopolymers that are used for post-transcriptional gene regulation and act as endogenous defenses against attack from viruses and dsRNA parasites. The siRNA field is making advances for ... -
Synthesis of internal amide bond short interfering RNAs (siRNAs) and investigation of their gene silencing properties
(2012-10-01)Cancer is a leading cause of death worldwide, accounting for around 13% of all death [1]. Traditional cancer therapeutics usually require careful selection of one or more intervention, such as surgery, radiotherapy, and ... -
Synthesis, characterization and biological investigation of self-delivering and modified short interfering RNAs (siRNAs)
(2021-07-01)Aberrant gene expression is a hallmark of disease, so it is of great interest to develop targeted therapies that provide a means to regulate gene expression. The RNA interference pathway serves as a natural defense system ... -
Synthesizing existing evidence and leveraging expert opinions to develop a university, for-profit, and not-for-profit organization partnership model to address health professions education gaps through simulation-based education
(2023-12-01)Healthcare providers in rural and remote (R&R) areas of Canada do not have the same access to skills development and maintenance opportunities as those in urban areas. Simulation-based education (SBE) is an optimal technique ... -
Synthesizing play: exploring the use of artificial intelligence to evaluate game user experience
(2020-03-01)Digital games are a complex interactive medium providing a multitude of different experiences. The field of games user research (GUR) is dedicated to investigating and optimizing user experience in games. Such inquiries ... -
System for evaluating effects of immersion in molten copper chloride salts on corrosion resistant coatings
(2014-12-01)Hydrogen, as one of the best alternative energy carrier candidates, is easier to sustain than fossil fuel. Hydrogen demand has significantly increased as a clean energy carrier. The Cu-Cl cycle is one of the capable ... -
A system framework for non-intrusive monitoring of HMI states for detecting human-in-the-loop error precursors
(2020-04-01)Past industrial accidents suggest that increased automation has had an adverse effect on operator situational awareness (SA) and Human-in-the-Loop (HITL) errors. More so, any current automation is not yet capable of providing ... -
System integration and optimization of copper-chlorine thermochemical cycle with various options for hydrogen production
(2013-08-01)The Copper-Chlorine (Cu-Cl) thermochemical water splitting cycle is one of the most attractive alternative thermochemical cycles for clean hydrogen production due to its lower temperature requirement and better overall ... -
A systematic review examining the effects of mHealth interventions on dietary adherence in patients with cardiovascular diseases
(2022-04-01)A systematic review was conducted to determine if diet-focused mHealth interventions are effective for supporting dietary adherence in patients with cardiovascular disease (CVD), a population where nonadherence is common. ... -
Systems and models for secure fallback authentication
(2018-12-01)Fallback authentication (FA) techniques such as security questions, Email resets, and SMS resets have significant security flaws that easily undermine the primary method of authentication. Security questions have been shown ...