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Immunomodulatory activity of Lacticaseibacillus rhamnosus R0011: analysis of secretome-mediated impacts on innate immune outcomes in intestinal epithelial cells and antigen presenting cells
(2021-12-01)
Certain lactic acid bacteria (LAB), such as Lacticaseibacillus rhamnosus R0011, are associated with immune modulatory activities including down-regulation of pro-inflammatory gene transcription and expression. While host ...
Development and characterization of chemical modifications for siRNA strand selection
(2021-12-01)
Small interfering RNA (siRNA) are non-coding, double-stranded RNA that enable efficient gene silencing through RNA interference (RNAi) mechanisms. The primary effector of RNAi is an RNA-guided nuclease, Ago2, which selects ...
The quantum and electromagnetic process of photon emission by the hydrogen atom
(Physics Essay, 2021-04-07)
Light emitted from atoms during transitions of electrons from higher to lower discrete
states has the form of photons carrying energy and angular momentum. This paper considers the
process of emission of a single photon ...
The Role of Interactive Visualization in Fostering Trust in AI
(IEEE, 2021-12-10)
The increasing use of artificial intelligence (AI) technologies across application domains has prompted our society to pay closer attention to AI's trustworthiness, fairness, interpretability, and accountability. In order ...
A Framework for Interactive Conference Posters
(2021-05-25)
In this paper, we present a complete framework for extending conference posters with interactive content. Poster content will become interactive, allowing viewers to manipulate visualizations, and save them for later. We ...
The synthesis and in vivo evaluation of chemically modified siRNAs that contain red-shifted internal azobenzene derivative spacers for selective and tunable photocontrol of activity without UV light
(2021-08-01)
Short interfering RNAs (siRNAs) are biopolymers that are used for post-transcriptional gene regulation and act as endogenous defenses against attack from viruses and dsRNA parasites. The siRNA field is making advances for ...
Investigating the distribution of Nitellopsis obtusa in Ontario Lakes and its role as an ecosystem engineer
(2021-08-01)
Nitellopsis obtusa is a non-native macrophyte introduced into the Laurentian Great Lakes in 1974. Over the last decade, increasing reports emerged for N. obtusa within lakes in the Great Lakes Basin. Despite N. obtusa being ...
A deep learning approach to focal cortical dysplasia segmentation in children with medically intractable epilepsy
(2021-08-01)
Paediatric epilepsy is one of the most common neurological disorders and has major impact on the cognition and quality of life of children. Focal Cortical Dysplasia (FCD) is one of the most common causes of medically ...
Approaching Humanities Questions Using Slow Visual Search Interfaces
(2021-06-01)
In this paper we discuss a visual search system that was designed and implemented for humanities scholars to ask questions of large document corpora. The system allows searches to be specified through traditional search, ...
Visualization, Digital Humanities, and the Problem of Instrumentalism
(2021-06-01)
In this paper we present the concept of “slow analytics” that attempts to ridge the gap between humanities tasks and visualization. Often within Technological disciplines the pursuit of speed and efficiency are paramount. ...