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Now showing items 51-60 of 144
On deep learning in physics
(2021-04-01)
Machine learning, and most notably deep neural networks, have seen unprecedented success in recent years due to their ability to learn complex nonlinear mappings by ingesting large amounts of data through the process of ...
Development and characterization of chemical modifications for siRNA strand selection
(2021-12-01)
Small interfering RNA (siRNA) are non-coding, double-stranded RNA that enable efficient gene silencing through RNA interference (RNAi) mechanisms. The primary effector of RNAi is an RNA-guided nuclease, Ago2, which selects ...
A mixed-method approach to analyze the robustness of natural language processing classifiers
(2021-04-01)
Natural language processing algorithms (NLP) have become an essential approach for processing large amounts of textual information with applications such as spam, phishing and content moderation. Malicious actors can craft ...
The synthesis and in vivo evaluation of chemically modified siRNAs that contain red-shifted internal azobenzene derivative spacers for selective and tunable photocontrol of activity without UV light
(2021-08-01)
Short interfering RNAs (siRNAs) are biopolymers that are used for post-transcriptional gene regulation and act as endogenous defenses against attack from viruses and dsRNA parasites. The siRNA field is making advances for ...
A deep learning approach to focal cortical dysplasia segmentation in children with medically intractable epilepsy
(2021-08-01)
Paediatric epilepsy is one of the most common neurological disorders and has major impact on the cognition and quality of life of children. Focal Cortical Dysplasia (FCD) is one of the most common causes of medically ...
A graph-based real-time spatial sound framework
(2020-01-01)
Given the importance of sound, and our ability to localize sound sources in three-dimensions in the real world, incorporating spatial sound in virtual environments can help increase realism, improve the sense of “presence”, ...
Comparing exercise responses to high intensity interval training between adults with and without asthma
(2020-06-01)
Exercise induced bronchoconstriction (EIBC) occurs in response to high ventilations during exercise, which cools and dries the airways, triggering an inflammatory cascade. High intensity interval training (HIIT) is associated ...
Computational methods for medical image registration
(2021-04-01)
A significant amount of research has been dedicated to the improvement of techniques in the field of medical image analysis. Imaging modalities have been improved and new acquisition methods have been introduced to reveal ...
Adaptive serious games for computer science education
(2020-10-01)
Serious games have the potential to effectively engage students to learn, however, these games tend to struggle accommodating learners with diverse abilities and needs. Furthermore, customizing a serious game to the ...
Investigating the distribution of Nitellopsis obtusa in Ontario Lakes and its role as an ecosystem engineer
(2021-08-01)
Nitellopsis obtusa is a non-native macrophyte introduced into the Laurentian Great Lakes in 1974. Over the last decade, increasing reports emerged for N. obtusa within lakes in the Great Lakes Basin. Despite N. obtusa being ...