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Now showing items 71-80 of 110
Development of Non-covalent Chemical Probes for μ, δ and κ Opioid Receptors
(2020-12-01)
Opioids are well-known pain relievers and one of several therapeutic options for pain management. Although opioids are very effective analgesics, continued use and abuse can lead to physical dependence and withdrawal ...
A big data and online health analytics framework extended to integrate clinical and countermeasure decision support
(2022-03-01)
Computing frameworks that utilize big data analytics to support Clinical Decision Support Systems (CDSS) have proven to impact human lives in applications on Earth and in space. In the application of Space Medicine Decision ...
Towards molecular reconstruction in Coulomb explosion imaging
(2021-02-01)
The interaction of a fast laser with molecules at the femtosecond time scale, leads to the latter losing most of its valence electrons and become positively charged. The molecule which was initially in an equilibrium state, ...
The quantum and electromagnetic process of photon emission by the hydrogen atom
(Physics Essay, 2021-04-07)
Light emitted from atoms during transitions of electrons from higher to lower discrete
states has the form of photons carrying energy and angular momentum. This paper considers the
process of emission of a single photon ...
Development and characterization of chemical modifications for siRNA strand selection
(2021-12-01)
Small interfering RNA (siRNA) are non-coding, double-stranded RNA that enable efficient gene silencing through RNA interference (RNAi) mechanisms. The primary effector of RNAi is an RNA-guided nuclease, Ago2, which selects ...
Templated N-doped carbon materials for energy storage and conversion: synthesis and characterization studies
(2020-08-01)
Sustainable energy sources are necessary to decrease the environmental problems associated with fossil fuels. Modified mesoporous carbon materials have been studied with aims of improving the performance of energy conversion ...
Forward and reverse genetic approaches to investigate cellulose biosynthesis in Physcomitrium patens
(2021-04-01)
Cellulose biosynthesis is a common feature of land plants and involves multimeric complexes composed of cellulose synthase A (CESA) proteins and other structural proteins. The exact stoichiometry of CESA proteins and ...
MAVIDS: an intelligent intrusion detection system for autonomous unmanned aerial vehicles
(2021-07-01)
Unmanned Aerial Vehicles (UAVs) face a large threat landscape, being used in numerous industries in hostile environments while relying on wireless communication. As attacks against UAVs increase, an intelligent Intrusion ...
Investigation of KimiaNet's and DenseNet's deep features in lung cancer subtypes
(2020-12-01)
Deep neural networks (DNN) have extended applications in the _eld of digital pathology. One of which is to act as feature extractors for content-based image retrieval (CBIR) systems. Therefore, it is necessary to investigate ...
Synthesis, characterization and biological investigation of self-delivering and modified short interfering RNAs (siRNAs)
(2021-07-01)
Aberrant gene expression is a hallmark of disease, so it is of great interest to develop targeted therapies that provide a means to regulate gene expression. The RNA interference pathway serves as a natural defense system ...