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Characterizing immunomodulatory activity of lactic acid bacteria on cell types involved in innate immunity: analysis of the effects of Lactobacillus rhamnosus R0011-derived milk ferments on macrophage polarization and of secretome effects on intestinal epithelial cell cytokine production
(2015-07-01)
Probiotic lactic acid bacteria have been associated with a wide array of host-immune modulatory effects including down-regulation of pro-inflammatory gene transcription and expression following pro-inflammatory challenge, ...
Beyond the noise: an exploration of informative sound design in video games
(2015-08-01)
Informative sounds in video games are those that are played with a functional
purpose. These sounds are meant to inform the player of some change in the
state of the game, be it in their character’s status or something in ...
Molecular characterization of the interactions of the Resistance-Nodulation-Division Pump MexJK of Pseudomonas aeruginosa with outer membrane proteins OprM and OpmH.
(2013-08-01)
Pseudomonas aeruginosa is an important Gram-negative opportunistic pathogen, which has become a significant threat due to wide-spread antimicrobial resistance. Resistance Nodulation Division efflux pumps are important ...
Stability of heroin metabolites and oxycodone in rat hair and liver during decomposition
(2010-01-01)
The aim of this study was to investigate the influence of soft tissue decomposition on the stability of drugs incorporated in hair antemortem. Two burial trials were conducted: in the first trial, rats were administered ...
Synthesis and in vitro assessment of chemically modified siRNAs targeting BCL2 that contain 2'-ribose and triazole-linked backbone modifications
(2015-08-01)
Short interfering RNAs (siRNAs) are biomolecules used for post-transcriptional gene regulation, and therefore hold promise as a future therapeutic by silencing gene expression of overexpressed deleterious genes. Chemically ...
Transport-theory-equivalent diffusion coefficients for node-homogenized neutron diffusion problems in CANDU lattices
(2010-04-01)
Calculation of the neutron flux in a nuclear reactor core is ideally performed by solving the neutron transport equation for a detailed-geometry model using several tens of energy groups. However, performing such detailed ...
Synthesis and characterization of purely sulphonated and composite membranes for high temperature fuel cells
(2010-04-01)
Fuel cell technologies have developed high interest due to their ability to provide energy in an environmentally friendly method. Proton exchange membrane fuel cells (PEM-FCs) require a PEM for use, where the most accepted ...
Applications and numerical investigation of differential-algebraic equations
(2010-05-01)
Differential-algebraic equations (DAEs) result in many areas of science and engineer-
ing. In this thesis, numerical methods for solving DAEs are compared for two prob-
lems, energy-economic models and traffic flow models. ...
Stereoscopic depth axis interaction: A study of performance and engagement in stereoscopic 3D games.
(2014-01-01)
Game developers strive to maximize immersion and engagement,
to emotionally involve the audience in their material. One technique
used to increase engagement is the development of new technologies,
such as Stereoscopic ...
The role of urban wetland diversity and function in contaminant fate
(2011-08-01)
It is recognized that microbial transformations are the primary mechanism of organic contaminant removal in natural and constructed wetland systems. However, not much is known about urban wetland microbial communities or ...