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Development and characterization of chemical modifications for siRNA strand selection
(2021-12-01)
Small interfering RNA (siRNA) are non-coding, double-stranded RNA that enable efficient gene silencing through RNA interference (RNAi) mechanisms. The primary effector of RNAi is an RNA-guided nuclease, Ago2, which selects ...
Deep learning for islanding detection of grid-connected photovoltaic systems
(2021-01-01)
Over the past decade, the integration of renewable-based distribution energy resources within the smart distribution system has been steadily growing. Despite the numerous advantages of integrating these renewable energy ...
Forward and reverse genetic approaches to investigate cellulose biosynthesis in Physcomitrium patens
(2021-04-01)
Cellulose biosynthesis is a common feature of land plants and involves multimeric complexes composed of cellulose synthase A (CESA) proteins and other structural proteins. The exact stoichiometry of CESA proteins and ...
Modeling and analysis of metal cutting process using self-propelled rotary tools
(2021-02-01)
Machining difficult-to-cut materials is still one of the challenges facing different industries such as aerospace, nuclear and automotive sectors. That’s mainly because of the excessive heat generated, which affects the ...
Design of broad-band dual-polarized microstrip patch antennas with high port isolation for millimeter-wave 5G applications
(2021-01-01)
In this thesis, multiple broadband dual linearly polarized antennas are designed covering the frequency band for the next generation of 5G communications around 28 GHz. Dual polarization antennas are employed to increase ...
MAVIDS: an intelligent intrusion detection system for autonomous unmanned aerial vehicles
(2021-07-01)
Unmanned Aerial Vehicles (UAVs) face a large threat landscape, being used in numerous industries in hostile environments while relying on wireless communication. As attacks against UAVs increase, an intelligent Intrusion ...
A study of a novel design for efficient hydrolysis reactor for the Cu-Cl thermochemical hydrogen production cycle
(2021-06-01)
In this thesis, methods to optimize the Hydrolysis reactor for the Cu-Cl thermochemical Hydrogen production cycle were investigated. A simplified Hydrolysis reactor using simple off-the-shelf components was tested and found ...
Development of a method for genetic optimization of aerodynamic devices
(2021-06-01)
Driving stability, fuel efficiency and soiling reduction are important for modern vehicles. This thesis has developed a novel method for genetic optimization of aerodynamic devices for road vehicle applications with the ...
Parents’ perceptions of their children’s lie telling in the context of sibling relationships
(2021-08-01)
Familial influences on children’s deception are understudied. This thesis examined children’s lie telling in the context of sibling relationships by surveying parents on the types of lies told by children in the sibling ...
Synthesis, characterization and biological investigation of self-delivering and modified short interfering RNAs (siRNAs)
(2021-07-01)
Aberrant gene expression is a hallmark of disease, so it is of great interest to develop targeted therapies that provide a means to regulate gene expression. The RNA interference pathway serves as a natural defense system ...