Browsing Doctoral Dissertations by Title
Now showing items 10-29 of 71
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Calculating thermochemical equilibrium for multiphysics simulations of nuclear materials : development of yellowjacket gibbs energy minimiser
(2022-11-01)Nuclear fuels and structural materials are highly complex systems that are remarkably challenging to understand and model. Material behaviours are influenced by multiple physical phenomena such as mechanics, chemistry, ... -
Characterization of the ACC-1 Family of cys-loop ligand gated ion channels from the parasitic nematode Haemonchus contortus.
(2020-12-01)Nematode cys-loop ligand-gated ion channels (LGICs) have been extensively studied for decades because of their role in current anthelmintic action and potential as targets for future drugs. Many families of cys loop receptors ... -
Cognitive function during exertional heat stress assessed using traditional and serious game technology
(2016-06-01)Firefighting is a physically demanding occupation requiring intermittent bouts of work resulting in increased levels of cardiovascular and thermal strain, while making decisions requiring higher order cognitive abilities ... -
Community-oriented architecture for smart cities
(2017-12-01)With the widespread use of smartphone devices, a surge in mobile sensing, progress in wireless communication and networking techniques, as well as the development of the Internet of Things (IoT) and cloud computing, ... -
Comparing exercise responses to high intensity interval training between adults with and without asthma
(2020-06-01)Exercise induced bronchoconstriction (EIBC) occurs in response to high ventilations during exercise, which cools and dries the airways, triggering an inflammatory cascade. High intensity interval training (HIIT) is associated ... -
Computational methods for medical image registration
(2021-04-01)A significant amount of research has been dedicated to the improvement of techniques in the field of medical image analysis. Imaging modalities have been improved and new acquisition methods have been introduced to reveal ... -
CORE: a framework for the automatic repair of concurrency bugs
(2015-01-01)Desktop computers now contain 2, 4 or even 8 processors. To benefit from them programs must be written to work in parallel. If writing good code is hard, writing good parallel code is much harder. Parallelization adds ... -
A deep learning approach to focal cortical dysplasia segmentation in children with medically intractable epilepsy
(2021-08-01)Paediatric epilepsy is one of the most common neurological disorders and has major impact on the cognition and quality of life of children. Focal Cortical Dysplasia (FCD) is one of the most common causes of medically ... -
Determining the impact of carrion decomposition on soil microbial activity levels and community composition.
(2013-12-01)The ubiquitous nature of microorganisms and their specificity to certain locations make them potentially useful for forensic investigators. Advances in microbial profiling techniques have made it possible to compare microbial ... -
Development and characterization of chemical modifications for siRNA strand selection
(2021-12-01)Small interfering RNA (siRNA) are non-coding, double-stranded RNA that enable efficient gene silencing through RNA interference (RNAi) mechanisms. The primary effector of RNAi is an RNA-guided nuclease, Ago2, which selects ... -
Development of Non-covalent Chemical Probes for μ, δ and κ Opioid Receptors
(2020-12-01)Opioids are well-known pain relievers and one of several therapeutic options for pain management. Although opioids are very effective analgesics, continued use and abuse can lead to physical dependence and withdrawal ... -
DL-based defense against polymorphic network attacks
(2024-01-01)Network security is of vital importance in our world dominated by internet systems. These systems are vulnerable to large-scale rapidly evolving attacks by sophisticated cyber attackers who can have an upper edge over the ... -
Dynamic probabilistic network protection in large-scale failure scenarios
(2015-01-01)Large-scale failure resulting from natural disasters or intentional attacks is now considered a serious risk for communication network infrastructure. In these events, simultaneous damages in several links and nodes may ... -
Dynamic square patterns in two dimensional neural fields
(2015-07-29)The goal of this thesis is to study the emergence of spatiotemporal waves in neural field models. Neural field models aim to describe the activity of populations of neurons at a mesoscopic scale, considering averaged ... -
A dynamic visual analytics framework for complex temporal environments
(2016-08-01)Introduction: Data streams are produced by sensors that sample an external system at a periodic interval. As the cost of developing sensors continues to fall, an increasing number of data stream acquisition systems have ... -
The ecotoxicological effects of metformin and its metabolite, guanylurea, on Japanese medaka (Oryzias latipes)
(2018-08-01)Human pharmaceutical waste threatens many natural processes of non-target aquatic organisms, through the introduction of such contaminants into the environment. Pharmaceuticals are a large and diverse groups of medicinal ... -
The effect of experimental pain on neural function and motor learning
(2017-04-01)This thesis investigated whether acute experimental pain interacts with motor learning acquisition to create adaptive and maladaptive changes in neural function. The first study consisted of two experiments where we ... -
The Effects of 17α-Ethinylestradiol (EE2) and Hydroxypropyl-β-Cyclodextrin (HPβCD) on the heart rate and metabolism of Embryonic Japanese Medaka (Oryzias latipes)
(2019-04-01)Estrogen toxicity has been an area of priority in aquatic toxicology over the last 20 years. The toxicity of a known estrogen mimic, 17α-ethinylestradiol (EE2), has been attributed to classical estrogen signaling within ... -
Effects of dietary fermentable material on innate and adaptive immune measures in male and female rats under resting and immunized conditions
(2015-02-01)Sex-based differences in immune parameters are well recognized, and recent evidence suggests differences in microbiota composition between sexes, necessitating assessment of effects of dietary fermentable material (DFM) ... -
Elucidation of the lipid degradation process in soft tissue and fluid during decomposition, in the presence and absence of insects.
(2014-08-01)Decomposition has been extensively studied in the presence of insects, however the process in the absence of insects has been considerably less documented. In this study, the decomposition process was compared between ...